Plerixafor and G-CSF for autologous stem cell mobilization in AL amyloidosis

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Autologous Stem Cell Transplant for AL Amyloidosis

AL amyloidosis is caused by clonal plasma cells that produce immunoglobulin light chains which misfold and get deposited as amyloid fibrils. Therapy directed against the plasma cell clone leads to clinical benefit. Melphalan and corticosteroids have been the mainstay of treatment for a number of years and the recent availability of other effective agents (IMiDs and proteasome inhibitors) has in...

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Diabetes Limits Stem Cell Mobilization Following G-CSF but Not Plerixafor

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Long-Term Outcome after Autologous Stem Cell Transplantation with Adequate Peripheral Blood Stem Cell Mobilization Using Plerixafor and G-CSF in Poor Mobilizer Lymphoma and Myeloma Patients

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CLINICAL TRIALS AND OBSERVATIONS Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma

1Washington University, St Louis, MO; 2Abramson Cancer Center of the University of Pennsylvania, Philadelphia; 3City of Hope Comprehensive Cancer Center, Duarte, CA; 4Mayo Clinic, Rochester, MN; 5Loyola University, Chicago, IL; 6Emory University, Atlanta, GA; 7Oregon Health & Science University, Portland; 8M. D. Anderson Cancer Center, Houston, TX; 9Universitätsklinikum Heidelberg, Heidelberg, ...

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ژورنال

عنوان ژورنال: Bone Marrow Transplantation

سال: 2014

ISSN: 0268-3369,1476-5365

DOI: 10.1038/bmt.2014.117